Heart Stem Cell Research Program

Giving a patient s own cardiac stem cells late after a heart attack.

Heart stem cell research program.

The heart research program is led by a multidisciplinary team of experts within cedars sinai medical center. A new treatment using stem cells which have the potential to grow into a variety of heart cell types could potentially repair and regenerate damaged heart tissue. Both embryonic stem cells and induced pluripotent stem cells mature cells that are manipulated back to a stem cell state can be harnessed to create new heart cells. This clinical trial will help determine the safety and feasibility of using cell based regenerative therapy for individuals with declining single right ventricles.

Jim dearing of louisville ky one of the first men in the world to receive heart stem cells might have helped start a medical revolution that could lead to a cure for heart failure. It was fortuitous timing. The difficulty is that the heart cells made with stem cells resemble the heart cells of an infant rather than adult heart cells. Clinical trials focus on using cardiac stem cells from donors to treat heart attack weakened hearts and advanced heart failure.

Learn about their goals expertise and more. Beatty was an ideal candidate for a clinical trial and soon received an infusion of stem cells derived from his own heart tissue making him the second patient in the world to undergo the procedure. Medstar heart vascular institute has enrolled its first patient to a clinical trial to determine whether cardiac stem cells reduce inflammation enough to improve heart function in patients with heart failure severe enough to require a left ventricular assist device or lvad stemvad is a randomized double blinded placebo controlled study that will assess the effects of. In a study published last february in the lancet researchers treated 17 heart attack patients with an infusion of stem cells taken from their own hearts.

California s first of its kind state program to fund stem cell research is running out of money and supporters want voters to provide a 5 5 billion infusion. Since the cedars sinai team completed the world s first cardiac stem cell infusion in 2009 additional insights have emerged from this and related work including the discovery in animals that iron infused cardiac stem cells can be guided with a magnet to damaged areas of the heart dramatically increasing their retention and healing potential. Johns hopkins patient bill beatty was the second person in the world to receive stem cells derived from his own heart tissue.